Does the combination of stress perfusion and delayed-enhancement MRI improve the detection of CAD?
Santo Dellegrottaglie and Zahi A Fayad*
Correspondence *Imaging Science Laboratories, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1234, New York, NY 10029, USA
Email zahi.fayad@mssm.edu
This article has no abstract so we have provided the first paragraph of the full text.
Recent studies on stress perfusion cardiac MRI have demonstrated significant improvements in the overall diagnostic performance of this technique for the detection of CAD. These improvements have largely been a consequence of increased spatial and temporal resolution obtained with the introduction of advanced hardware equipment (i.e.
1-Tesla scanners and surface phased-array coils) and new imaging sequences for cardiac MRI (i.e. fast gradient-echo imaging with magnetization preparation schemes and parallel imaging).1, 2 Nevertheless, perfusion cardiac MRI techniques still have limited specificity in the recognition of myocardial perfusion defects, as initial multicenter studies have shown.3 Dark artifacts can frequently appear in the subendocardial layer of the myocardium, thereby increasing the number of false positive results.
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