Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2005) 2, 436-437
doi:10.1038/ncpcardio0285  
| Published online: 17 August 2005

Does coating stents with titanium oxynitride reduce restenosis?

Rebecca Ireland

This article has no abstract so we have provided the first paragraph of the full text.

Restenosis due to neointimal proliferation is a major limitation of percutaneous coronary interventions. Stent surface material can influence restenosis rates, with gold-coated stents leading to an increased risk of restenosis; similarly, stainless steel stents increase the risk of restenosis in patients who are allergic to nickel. The single-blind, randomized, prospective, TiNOX study was performed at centers in Switzerland and Germany, and compared the safety and efficacy of stents coated with titanium oxynitride (TiNOX) with that of uncoated stainless steel stents in patients with de novo, native coronary artery lesions.

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