Jonathan C. Ryan et al.

Distributed surface impurities influence albedo in Greenland ice sheet

Latest Research

  • Article | | open

    Cyclic AMP and cGMP orchestrate a variety of cellular responses. Here, authors characterize the cGMP producing rhodopsin-guanylyl cyclase from C. anguillulae and derived adenylyl cyclase by a biochemical and structural approach which demonstrates the usability of these cyclases for optogenetic applications.

    • Ulrike Scheib
    • , Matthias Broser
    • , Oana M. Constantin
    • , Shang Yang
    • , Shiqiang Gao
    • , Shatanik Mukherjee
    • , Katja Stehfest
    • , Georg Nagel
    • , Christine E. Gee
    •  & Peter Hegemann
  • Article | | open

    The unique properties of 2D materials are affected by the discontinuities posed by the structure’s edge. Here, using atomic-resolution scanning transmission electron microscopy and ab initio molecular dynamics simulations, the authors image and explain the formation of specific edge structures on Mo1 x W x Se2 monolayers under different chemical conditions.

    • Xiahan Sang
    • , Xufan Li
    • , Wen Zhao
    • , Jichen Dong
    • , Christopher M. Rouleau
    • , David B. Geohegan
    • , Feng Ding
    • , Kai Xiao
    •  & Raymond R. Unocic
  • Article | | open

    The distinct genomic and epidemiological features of Chinese lung cancer patients suggest the presence of alternative causal mechanisms. Here, the authors present the genomic landscape of 149 Chinese NSCLC patients and reveal distinct mutational signatures associated with inflammatory microenvironments.

    • Cheng Wang
    • , Rong Yin
    • , Juncheng Dai
    • , Yayun Gu
    • , Shaohua Cui
    • , Hongxia Ma
    • , Zhihong Zhang
    • , Jiaqi Huang
    • , Na Qin
    • , Tao Jiang
    • , Liguo Geng
    • , Meng Zhu
    • , Zhening Pu
    • , Fangzhi Du
    • , Yuzhuo Wang
    • , Jianshui Yang
    • , Liang Chen
    • , Qianghu Wang
    • , Yue Jiang
    • , Lili Dong
    • , Yihong Yao
    • , Guangfu Jin
    • , Zhibin Hu
    • , Liyan Jiang
    • , Lin Xu
    •  & Hongbing Shen
  • Article | | open

    Photodynamic therapy has attracted interest in treating cancer but it is limited in hypoxic tumors due to a lack of oxygen. Here, the authors describe a nano-composite capable of generating oxygen under near-infrared light for improved photodynamic and chemotherapy for treating cancer.

    • Shuting Xu
    • , Xinyuan Zhu
    • , Chuan Zhang
    • , Wei Huang
    • , Yongfeng Zhou
    •  & Deyue Yan
  • Article | | open

    Historical acute promyelocytic leukemia patients treated with retinoic acid and chemotherapy sometimes did relapse. Here the authors performed exome sequencing on 64 patient's samples from diagnosis/relapse/remission and show relapse associates either with cooperating oncogenes at diagnosis, or with unexpected persistence of ancestral pre-leukemic clones.

    • Jacqueline Lehmann-Che
    • , Cécile Bally
    • , Eric Letouzé
    • , Caroline Berthier
    • , Hao Yuan
    • , Florence Jollivet
    • , Lionel Ades
    • , Bruno Cassinat
    • , Pierre Hirsch
    • , Arnaud Pigneux
    • , Marie-Joelle Mozziconacci
    • , Scott Kogan
    • , Pierre Fenaux
    •  & Hugues de Thé
  • Article | | open

    Myotube formation by fusion of myoblasts is essential for skeletal muscle formation, but which molecules regulate this process remains elusive. Here authors identify the mechanosensitive PIEZO1 channel as a key element, whose activity is regulated by phosphatidylserine during myotube formation.

    • Masaki Tsuchiya
    • , Yuji Hara
    • , Masaki Okuda
    • , Karin Itoh
    • , Ryotaro Nishioka
    • , Akifumi Shiomi
    • , Kohjiro Nagao
    • , Masayuki Mori
    • , Yasuo Mori
    • , Junichi Ikenouchi
    • , Ryo Suzuki
    • , Motomu Tanaka
    • , Tomohiko Ohwada
    • , Junken Aoki
    • , Motoi Kanagawa
    • , Tatsushi Toda
    • , Yosuke Nagata
    • , Ryoichi Matsuda
    • , Yasunori Takayama
    • , Makoto Tominaga
    •  & Masato Umeda

News & Comment

  • Editorial | | open

    The Sc2.0 project has set out to synthesise the Saccharomyces cerevisiae genome, with each chromosome redesigned along agreed principles. In this collection of papers, the researchers involved show how SCRaMbLE—Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution—can be used to rapidly reorganise the genome.

  • Editorial | | open

    Today, on the 16th May, we celebrate the first International Day of Light, which UNESCO proclaimed late last year. We celebrate the central role light and light-based technologies play in our lives and consider how they can be beneficial to humanity through sustainable lighting, renewable energy and improved health care.

  • Editorial | | open

    Epidemiology dates back to the Age of Pericles in 5th Century B.C., but its standing as a ‘true’ science in 21st century is often questioned. This is unexpected, given that epidemiology directly impacts lives and our reliance on it will only increase in a changing world.

  • Editorial | | open

    Vaccination has successfully reduced the burden of infectious diseases worldwide, but stagnating immunization coverage and lack of effective vaccines for many endemic and newly emerging pathogens pose a threat to sustainable global health. In light of World Immunization Week 2018, which highlights the importance of high vaccination coverage, Nature Communications is taking stock of current advances and barriers in vaccine development and distribution.

Focus

Condensed-Matter Physics

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Condensed-Matter Physics

Editors' Highlights: Each month our editors select a small number of Articles recently published in Nature Communications that they believe are particularly interesting or important.

Richard Brierley, Wei Fan, Yu Gong and Silvia Milana

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