Toshiya Ando et al.

Genetic basis for colour patterns of ladybird beetles

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  • Article | | open

    Urinary tract infections are a common side effect of urethral catheters. Here, the authors report on the development of antibiotic loaded NPs with functional polymer coatings which attach too and are removed by motile bacteria to trigger the release of antibiotic.

    • Shengtao Lu
    • , Wuguo Bi
    • , Quanchao Du
    • , Sheetal Sinha
    • , Xiangyang Wu
    • , Arnold Subrata
    • , Surajit Bhattacharjya
    • , Bengang Xing
    •  & Edwin K. L. Yeow
  • Article | | open

    Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.

    • Dennis Pägelow
    • , Chintan Chhatbar
    • , Andreas Beineke
    • , Xiaokun Liu
    • , Andreas Nerlich
    • , Kira van Vorst
    • , Manfred Rohde
    • , Ulrich Kalinke
    • , Reinhold Förster
    • , Stephan Halle
    • , Peter Valentin-Weigand
    • , Mathias W. Hornef
    •  & Marcus Fulde
  • Article | | open

    Progressive diseases tend to be heterogeneous in their underlying aetiology mechanism, disease manifestation, and disease time course. Here, Young and colleagues devise a computational method to account for both phenotypic heterogeneity and temporal heterogeneity, and demonstrate it using two neurodegenerative disease cohorts.

    • Alexandra L Young
    • , Razvan V Marinescu
    • , Neil P Oxtoby
    • , Martina Bocchetta
    • , Keir Yong
    • , Nicholas C Firth
    • , David M Cash
    • , David L Thomas
    • , Katrina M Dick
    • , Jorge Cardoso
    • , John van Swieten
    • , Barbara Borroni
    • , Daniela Galimberti
    • , Mario Masellis
    • , Maria Carmela Tartaglia
    • , James B Rowe
    • , Caroline Graff
    • , Fabrizio Tagliavini
    • , Giovanni B Frisoni
    • , Robert Laforce Jr
    • , Elizabeth Finger
    • , Alexandre de Mendonça
    • , Sandro Sorbi
    • , Jason D Warren
    • , Sebastian Crutch
    • , Nick C Fox
    • , Sebastien Ourselin
    • , Jonathan M Schott
    • , Jonathan D Rohrer
    • , Daniel C Alexander
    • , Christin Andersson
    • , Silvana Archetti
    • , Andrea Arighi
    • , Luisa Benussi
    • , Giuliano Binetti
    • , Sandra Black
    • , Maura Cosseddu
    • , Marie Fallström
    • , Carlos Ferreira
    • , Chiara Fenoglio
    • , Morris Freedman
    • , Giorgio G Fumagalli
    • , Stefano Gazzina
    • , Roberta Ghidoni
    • , Marina Grisoli
    • , Vesna Jelic
    • , Lize Jiskoot
    • , Ron Keren
    • , Gemma Lombardi
    • , Carolina Maruta
    • , Lieke Meeter
    • , Simon Mead
    • , Rick van Minkelen
    • , Benedetta Nacmias
    • , Linn Öijerstedt
    • , Alessandro Padovani
    • , Jessica Panman
    • , Michela Pievani
    • , Cristina Polito
    • , Enrico Premi
    • , Sara Prioni
    • , Rosa Rademakers
    • , Veronica Redaelli
    • , Ekaterina Rogaeva
    • , Giacomina Rossi
    • , Martin Rossor
    • , Elio Scarpini
    • , David Tang-Wai
    • , Hakan Thonberg
    • , Pietro Tiraboschi
    • , Ana Verdelho
    • , Michael W Weiner
    • , Paul Aisen
    • , Ronald Petersen
    • , Clifford R Jack
    • , William Jagust
    • , John Q Trojanowki
    • , Arthur W Toga
    • , Laurel Beckett
    • , Robert C Green
    • , Andrew J Saykin
    • , John Morris
    • , Leslie M Shaw
    • , Zaven Khachaturian
    • , Greg Sorensen
    • , Lew Kuller
    • , Marc Raichle
    • , Steven Paul
    • , Peter Davies
    • , Howard Fillit
    • , Franz Hefti
    • , Davie Holtzman
    • , M Marcel Mesulam
    • , William Potter
    • , Peter Snyder
    • , Adam Schwartz
    • , Tom Montine
    • , Ronald G Thomas
    • , Michael Donohue
    • , Sarah Walter
    • , Devon Gessert
    • , Tamie Sather
    • , Gus Jiminez
    • , Danielle Harvey
    • , Matthew Bernstein
    • , Paul Thompson
    • , Norbert Schuff
    • , Bret Borowski
    • , Jeff Gunter
    • , Matt Senjem
    • , Prashanthi Vemuri
    • , David Jones
    • , Kejal Kantarci
    • , Chad Ward
    • , Robert A Koeppe
    • , Norm Foster
    • , Eric M Reiman
    • , Kewei Chen
    • , Chet Mathis
    • , Susan Landau
    • , Nigel J Cairns
    • , Erin Householder
    • , Lisa Taylor-Reinwald
    • , Virginia Lee
    • , Magdalena Korecka
    • , Michal Figurski
    • , Karen Crawford
    • , Scott Neu
    • , Tatiana M Foroud
    • , Steven Potkin
    • , Li Shen
    • , Kelley Faber
    • , Sungeun Kim
    • , Kwangsik Nho
    • , Leon Thal
    • , Neil Buckholtz
    • , Marylyn Albert
    • , Richard Frank
    • , John Hsiao
    • , Jeffrey Kaye
    • , Joseph Quinn
    • , Betty Lind
    • , Raina Carter
    • , Sara Dolen
    • , Lon S Schneider
    • , Sonia Pawluczyk
    • , Mauricio Beccera
    • , Liberty Teodoro
    • , Bryan M Spann
    • , James Brewer
    • , Helen Vanderswag
    • , Adam Fleisher
    • , Judith L Heidebrink
    • , Joanne L Lord
    • , Sara S Mason
    • , Colleen S Albers
    • , David Knopman
    • , Kris Johnson
    • , Rachelle S Doody
    • , Javier Villanueva-Meyer
    • , Munir Chowdhury
    • , Susan Rountree
    • , Mimi Dang
    • , Yaakov Stern
    • , Lawrence S Honig
    • , Karen L Bell
    • , Beau Ances
    • , Maria Carroll
    • , Sue Leon
    • , Mark A Mintun
    • , Stacy Schneider
    • , Angela Oliver
    • , Daniel Marson
    • , Randall Griffith
    • , David Clark
    • , David Geldmacher
    • , John Brockington
    • , Erik Roberson
    • , Hillel Grossman
    • , Effie Mitsis
    • , Leyla de Toledo-Morrell
    • , Raj C Shah
    • , Ranjan Duara
    • , Daniel Varon
    • , Maria T Greig
    • , Peggy Roberts
    • , Marilyn Albert
    • , Chiadi Onyike
    • , Daniel D’Agostino
    • , Stephanie Kielb
    • , James E Galvin
    • , Brittany Cerbone
    • , Christina A Michel
    • , Henry Rusinek
    • , Mony J de Leon
    • , Lidia Glodzik
    • , Susan De Santi
    • , P Murali Doraiswamy
    • , Jeffrey R Petrella
    • , Terence Z Wong
    • , Steven E Arnold
    • , Jason H Karlawish
    • , David Wolk
    • , Charles D Smith
    • , Greg Jicha
    • , Peter Hardy
    • , Partha Sinha
    • , Elizabeth Oates
    • , Gary Conrad
    • , Oscar L Lopez
    • , MaryAnn Oakley
    • , Donna M Simpson
    • , Anton P Porsteinsson
    • , Bonnie S Goldstein
    • , Kim Martin
    • , Kelly M Makino
    • , M Saleem Ismail
    • , Connie Brand
    • , Ruth A Mulnard
    • , Gaby Thai
    • , Catherine Mc-Adams-Ortiz
    • , Kyle Womack
    • , Dana Mathews
    • , Mary Quiceno
    • , Ramon Diaz-Arrastia
    • , Richard King
    • , Myron Weiner
    • , Kristen Martin-Cook
    • , Michael DeVous
    • , Allan I Levey
    • , James J Lah
    • , Janet S Cellar
    • , Jeffrey M Burns
    • , Heather S Anderson
    • , Russell H Swerdlow
    • , Liana Apostolova
    • , Kathleen Tingus
    • , Ellen Woo
    • , Daniel Hs Silverman
    • , Po H Lu
    • , George Bartzokis
    • , Neill R Graff-Radford
    • , Francine Parfitt
    • , Tracy Kendall
    • , Heather Johnson
    • , Martin R Farlow
    • , Ann Marie Hake
    • , Brandy R Matthews
    • , Scott Herring
    • , Cynthia Hunt
    • , Christopher H van Dyck
    • , Richard E Carson
    • , Martha G MacAvoy
    • , Howard Chertkow
    • , Howard Bergman
    • , Chris Hosein
    • , Bojana Stefanovic
    • , Curtis Caldwell
    • , Ging-Yuek Robin Hsiung
    • , Howard Feldman
    • , Benita Mudge
    • , Michele Assaly
    • , Andrew Kertesz
    • , John Rogers
    • , Charles Bernick
    • , Donna Munic
    • , Diana Kerwin
    • , Marek-Marsel Mesulam
    • , Kristine Lipowski
    • , Chuang-Kuo Wu
    • , Nancy Johnson
    • , Carl Sadowsky
    • , Walter Martinez
    • , Teresa Villena
    • , Raymond Scott Turner
    • , Kathleen Johnson
    • , Brigid Reynolds
    • , Reisa A Sperling
    • , Keith A Johnson
    • , Gad Marshall
    • , Meghan Frey
    • , Barton Lane
    • , Allyson Rosen
    • , Jared Tinklenberg
    • , Marwan N Sabbagh
    • , Christine M Belden
    • , Sandra A Jacobson
    • , Sherye A Sirrel
    • , Neil Kowall
    • , Ronald Killiany
    • , Andrew E Budson
    • , Alexander Norbash
    • , Patricia Lynn Johnson
    • , Joanne Allard
    • , Alan Lerner
    • , Paula Ogrocki
    • , Leon Hudson
    • , Evan Fletcher
    • , Owen Carmichael
    • , John Olichney
    • , Charles DeCarli
    • , Smita Kittur
    • , Michael Borrie
    • , T-Y Lee
    • , Rob Bartha
    • , Sterling Johnson
    • , Sanjay Asthana
    • , Cynthia M Carlsson
    • , Steven G Potkin
    • , Adrian Preda
    • , Dana Nguyen
    • , Pierre Tariot
    • , Stephanie Reeder
    • , Vernice Bates
    • , Horacio Capote
    • , Michelle Rainka
    • , Douglas W Scharre
    • , Maria Kataki
    • , Anahita Adeli
    • , Earl A Zimmerman
    • , Dzintra Celmins
    • , Alice D Brown
    • , Godfrey D Pearlson
    • , Karen Blank
    • , Karen Anderson
    • , Robert B Santulli
    • , Tamar J Kitzmiller
    • , Eben S Schwartz
    • , Kaycee M Sink
    • , Jeff D Williamson
    • , Pradeep Garg
    • , Franklin Watkins
    • , Brian R Ott
    • , Henry Querfurth
    • , Geoffrey Tremont
    • , Stephen Salloway
    • , Paul Malloy
    • , Stephen Correia
    • , Howard J Rosen
    • , Bruce L Miller
    • , Jacobo Mintzer
    • , Kenneth Spicer
    • , David Bachman
    • , Stephen Pasternak
    • , Irina Rachinsky
    • , Dick Drost
    • , Nunzio Pomara
    • , Raymundo Hernando
    • , Antero Sarrael
    • , Susan K Schultz
    • , Laura L Boles Ponto
    • , Hyungsub Shim
    • , Karen Elizabeth Smith
    • , Norman Relkin
    • , Gloria Chaing
    • , Lisa Raudin
    • , Amanda Smith
    • , Kristin Fargher
    • , Balebail Ashok Raj
    • , Thomas Neylan
    • , Jordan Grafman
    • , Melissa Davis
    • , Rosemary Morrison
    • , Jacqueline Hayes
    • , Shannon Finley
    • , Karl Friedl
    • , Debra Fleischman
    • , Konstantinos Arfanakis
    • , Olga James
    • , Dino Massoglia
    • , J Jay Fruehling
    • , Sandra Harding
    • , Elaine R Peskind
    • , Eric C Petrie
    • , Gail Li
    • , Jerome A Yesavage
    • , Joy L Taylor
    •  & Ansgar J Furst
  • Article | | open

    Resistance to anti-HER2 therapy in breast cancer remains a major obstacle in the clinic. Here the authors performed a CRISPR-selective vulnerability screen to identify transaldoloase as a target that is synthetically lethal with HER2 inhibition in breast cancer cells.

    • Yi Ding
    • , Chang Gong
    • , De Huang
    • , Rui Chen
    • , Pinpin Sui
    • , Kevin H. Lin
    • , Gehao Liang
    • , Lifeng Yuan
    • , Handan Xiang
    • , Junying Chen
    • , Tao Yin
    • , Peter B. Alexander
    • , Qian-Fei Wang
    • , Er-Wei Song
    • , Qi-Jing Li
    • , Kris C. Wood
    •  & Xiao-Fan Wang
  • Article | | open

    Cognitive decline in Huntington’s disease (HD) may be due to impaired hippocampal synaptic plasticity. In this study the authors show that AMPA receptor surface diffusion, a key player in synaptic plasticity, is deregulated in multiple HD mouse models as a result of impaired BDNF signalling that underlies the memory deficits, and can be pharmacologically rescued.

    • Hongyu Zhang
    • , Chunlei Zhang
    • , Jean Vincent
    • , Diana Zala
    • , Caroline Benstaali
    • , Matthieu Sainlos
    • , Dolors Grillo-Bosch
    • , Sophie Daburon
    • , Françoise Coussen
    • , Yoon Cho
    • , Denis J. David
    • , Frederic Saudou
    • , Yann Humeau
    •  & Daniel Choquet
  • Article | | open

    Enabling concurrent, high throughput analysis of single nano particles would greatly increase the capacity to study size, composition and inter and intra particle population variance. Here, the authors present a comprehensive platform for single particle automated Raman trapping analysis without any target modification.

    • Jelle Penders
    • , Isaac J. Pence
    • , Conor C. Horgan
    • , Mads S. Bergholt
    • , Christopher S. Wood
    • , Adrian Najer
    • , Ulrike Kauscher
    • , Anika Nagelkerke
    •  & Molly M. Stevens

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