Jonathan C. Ryan et al.

Distributed surface impurities influence albedo in Greenland ice sheet

Latest Research

  • Article | | open

    A bottleneck in developing new anti-fibrosis therapies is the absence of suitable in vitro models that recapitulate key features of fibrogenesis. Here the authors develop a tissue-on-a-chip model of lung fibrosis and test the therapeutic efficacy of two recent FDA-approved drugs.

    • Mohammadnabi Asmani
    • , Sanjana Velumani
    • , Yan Li
    • , Nicole Wawrzyniak
    • , Isaac Hsia
    • , Zhaowei Chen
    • , Boris Hinz
    •  & Ruogang Zhao
  • Article | | open

    Benzofluorene-containing angucyclines, bacterial natural compounds with potential use as therapeutics/antibiotics, occur as dimers. Here, the authors elucidated the dimerization mechanism which turned out to work spontaneously, without enzymatic catalysis.

    • Chunshuai Huang
    • , Chunfang Yang
    • , Wenjun Zhang
    • , Liping Zhang
    • , Bidhan Chandra De
    • , Yiguang Zhu
    • , Xiaodong Jiang
    • , Chunyan Fang
    • , Qingbo Zhang
    • , Cheng-Shan Yuan
    • , Hung-wen Liu
    •  & Changsheng Zhang
  • Article | | open

    Smooth muscle cells (SMCs) invade atherosclerotic lesions and expand, contributing to plaque progression. Here Misra et al. show that SMC-derived plaque cells come from a single SMC and integrin β3 in SMCs and macrophages regulate the fate, expansion and migration of SMCs during plaque formation.

    • Ashish Misra
    • , Zhonghui Feng
    • , Rachana R. Chandran
    • , Inamul Kabir
    • , Noemi Rotllan
    • , Binod Aryal
    • , Abdul Q. Sheikh
    • , Ling Ding
    • , Lingfeng Qin
    • , Carlos Fernández-Hernando
    • , George Tellides
    •  & Daniel M. Greif
  • Article | | open

    Detrimental serrated plastic flow via dynamic strain aging (DSA) in conventionally processed nickel superalloys usually occurs during high temperature deformation. Here, the authors suppress DSA via a unique microstructure obtained using additive manufacturing and propose a new dislocation-arrest model in nickel superalloys.

    • Allison M. Beese
    • , Zhuqing Wang
    • , Alexandru D. Stoica
    •  & Dong Ma
  • Article | | open

    Strong non-resonant few-cycle laser pulses can be used to induce ultrafast phase-controllable currents along nanojunctions but the microscopic origin is unclear. Here, the authors present time-dependent quantum transport simulations that recover the experimental observations and offer an intuitive picture of the effect.

    • Liping Chen
    • , Yu Zhang
    • , GuanHua Chen
    •  & Ignacio Franco
  • Article | | open

    Acid-sensing ion channels (ASICs) sense changes in extracellular acidity with Ca2+ as an allosteric modulator and channel blocker. Here authors use electrophysiology and molecular dynamics simulation to identify the residue in ASIC3 which modulates proton sensitivity and contributes to the Ca2+ block.

    • Zhicheng Zuo
    • , Rachel N. Smith
    • , Zhenglan Chen
    • , Amruta S. Agharkar
    • , Heather D. Snell
    • , Renqi Huang
    • , Jin Liu
    •  & Eric B. Gonzales

News & Comment

  • Editorial | | open

    The Sc2.0 project has set out to synthesise the Saccharomyces cerevisiae genome, with each chromosome redesigned along agreed principles. In this collection of papers, the researchers involved show how SCRaMbLE—Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution—can be used to rapidly reorganise the genome.

  • Editorial | | open

    Today, on the 16th May, we celebrate the first International Day of Light, which UNESCO proclaimed late last year. We celebrate the central role light and light-based technologies play in our lives and consider how they can be beneficial to humanity through sustainable lighting, renewable energy and improved health care.

  • Editorial | | open

    Epidemiology dates back to the Age of Pericles in 5th Century B.C., but its standing as a ‘true’ science in 21st century is often questioned. This is unexpected, given that epidemiology directly impacts lives and our reliance on it will only increase in a changing world.

  • Editorial | | open

    Vaccination has successfully reduced the burden of infectious diseases worldwide, but stagnating immunization coverage and lack of effective vaccines for many endemic and newly emerging pathogens pose a threat to sustainable global health. In light of World Immunization Week 2018, which highlights the importance of high vaccination coverage, Nature Communications is taking stock of current advances and barriers in vaccine development and distribution.

Focus

Condensed-Matter Physics

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Condensed-Matter Physics

Editors' Highlights: Each month our editors select a small number of Articles recently published in Nature Communications that they believe are particularly interesting or important.

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