Luke J. Eberhart-Phillips et al.

Origins and consequences of adult sex ratios

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    Zika virus infection of pregnant women can cause congenital brain defects. Here, Coffey et al. establish a pregnant rhesus macaque model, using intravenous and intraamniotic route of infection, that reliably reproduces fetal neurologic defects of congenital Zika syndrome in humans.

    • Lark L. Coffey
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    • , Sallie Permar
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    • , Pietro Presicce
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    • , Kui Gao
    • , Robert Orr
    • , Tracy MacGill
    • , Michelle McClure
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    • , John H. Morrison
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    Myelodysplastic syndrome (MDS) is characterized by altered hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) regulation and reduction of miR-143 and miR-145 in some subtypes. Here the authors show that miR-143/145 loss leads to HSC depletion, HPC expansion and malignancy through Dab2 -mediated TGFβ pathway activation.

    • Jeffrey Lam
    • , Marion van den Bosch
    • , Joanna Wegrzyn
    • , Jeremy Parker
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    • , Sergio Martinez-Høyer
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    ‘Conformist bias’, in which individuals learn a common behavioural variant more often than expected by chance, has not been demonstrated convincingly in non-human animals. This study analyses song recordings and models of cultural evolution to show conformist bias in swamp sparrow populations.

    • Robert F. Lachlan
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    Single cell ATAC-seq (scATAC-seq) data reveals cellular level epigenetic heterogeneity but its application in delineating distinct subpopulations is still challenging. Here, the authors develop scABC, a statistical method for unsupervised clustering of scATAC-seq data and identification of open chromatin regions specific to cell identity.

    • Mahdi Zamanighomi
    • , Zhixiang Lin
    • , Timothy Daley
    • , Xi Chen
    • , Zhana Duren
    • , Alicia Schep
    • , William J. Greenleaf
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  • Article | | open

    Deciphering absolute configuration of individual molecules directly by visual inspection remains a highly attractive goal. Here, the authors determine the absolute configuration and orientation of a single [123]tetramantane molecule adsorbed on Cu(111) using low temperature atomic force microscopy with a CO-functionalized tip.

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    • , Marina Šekutor
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Condensed-Matter Physics

Editors' Highlights: Each month our editors select a small number of Articles recently published in Nature Communications that they believe are particularly interesting or important.

Richard Brierley, Wei Fan, Yu Gong and Silvia Milana

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