Dorothee Bornhorst et al.

Biomechanical signalling coordinates endocardial and myocardial growth in the zebrafish heart

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Physical sciences

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  • Article
    | Open Access

    Energy transfer in light harvesting complexes involves electronic, vibrational, and vibronic couplings which are challenging to resolve. Here the authors observe the time-evolution of vibronic coherences driving charge transfer in a photoexcited solvated transition metal complex by two- and three-dimensional electronic-vibrational spectroscopy.

    • James D. Gaynor
    • , Jason Sandwisch
    •  & Munira Khalil
  • Article
    | Open Access

    Fast ignition is an interesting scheme for nuclear fusion reaction. Here the authors show electron generation using intense short laser pulses and energy transport by coupling the laser energy to the imploded plasma core as in the ICF conditions.

    • T. Gong
    • , H. Habara
    • , K. Sumioka
    • , M. Yoshimoto
    • , Y. Hayashi
    • , S. Kawazu
    • , T. Otsuki
    • , T. Matsumoto
    • , T. Minami
    • , K. Abe
    • , K. Aizawa
    • , Y. Enmei
    • , Y. Fujita
    • , A. Ikegami
    • , H. Makiyama
    • , K. Okazaki
    • , K. Okida
    • , T. Tsukamoto
    • , Y. Arikawa
    • , S. Fujioka
    • , Y. Iwasa
    • , S. Lee
    • , H. Nagatomo
    • , H. Shiraga
    • , K. Yamanoi
    • , M. S. Wei
    •  & K. A. Tanaka
  • Article
    | Open Access

    Myeloid-derived growth factor (MYDGF) is an endoplasmic reticulum protein of therapeutic interest because it promotes tissue repair in a murine model of myocardial infarction. Here the authors present the NMR structure of human MYDGF and attribute function to a set of residues conserved in MYDGFs but not the vanin base domain, which has a similar fold.

    • Valeriu Bortnov
    • , Marco Tonelli
    • , Woonghee Lee
    • , Ziqing Lin
    • , Douglas S. Annis
    • , Omar N. Demerdash
    • , Alex Bateman
    • , Julie C. Mitchell
    • , Ying Ge
    • , John L. Markley
    •  & Deane F. Mosher

Earth and environmental sciences

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  • Article
    | Open Access

    Carbon dioxide removal technologies are often touted as a potential strategy to combat ocean acidification. However, the authors show here that these strategies are only effective when included as part of aggressive and rapid climate-action, undermining the idea of geoengineering as a panacea.

    • M. Hofmann
    • , S. Mathesius
    • , E. Kriegler
    • , D. P. van Vuuren
    •  & H. J. Schellnhuber
  • Article
    | Open Access

    Prior studies have examined fixed traits that correlate with plant invasiveness. Here the authors use a database of population matrices to compare demographic traits of invasive species in their native and invaded ranges, finding that demographic amplification is an important predictor of invasiveness.

    • Kim Jelbert
    • , Danielle Buss
    • , Jenni McDonald
    • , Stuart Townley
    • , Miguel Franco
    • , Iain Stott
    • , Owen Jones
    • , Roberto Salguero-Gómez
    • , Yvonne Buckley
    • , Tiffany Knight
    • , Matthew Silk
    • , Francesca Sargent
    • , Simon Rolph
    • , Phil Wilson
    •  & Dave Hodgson
  • Article
    | Open Access

    Photosynthesis generates reactive oxygen species that can damage cells. Here, the authors show that unicellular predators of photosynthetic prey have shared responses to photosynthetic oxidative stress and these may also have been important for the evolution of endosymbiosis.

    • Akihiro Uzuka
    • , Yusuke Kobayashi
    • , Ryo Onuma
    • , Shunsuke Hirooka
    • , Yu Kanesaki
    • , Hirofumi Yoshikawa
    • , Takayuki Fujiwara
    •  & Shin-ya Miyagishima

Biological sciences

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  • Article
    | Open Access

    Polymorphisms in LMO1 are associated with increased susceptibility to develop neuroblastoma. Here, the authors show that LMO1 directly induces the transcription factor ASCL1, which regulates the differentiation of neurons, demonstrating that ASCL1 is part of the adrenergic neuroblastoma core regulatory circuit.

    • Lu Wang
    • , Tze King Tan
    • , Adam D. Durbin
    • , Mark W. Zimmerman
    • , Brian J. Abraham
    • , Shi Hao Tan
    • , Phuong Cao Thi Ngoc
    • , Nina Weichert-Leahey
    • , Koshi Akahane
    • , Lee N. Lawton
    • , Jo Lynne Rokita
    • , John M. Maris
    • , Richard A. Young
    • , A. Thomas Look
    •  & Takaomi Sanda
  • Article
    | Open Access

    Myeloid-derived growth factor (MYDGF) is an endoplasmic reticulum protein of therapeutic interest because it promotes tissue repair in a murine model of myocardial infarction. Here the authors present the NMR structure of human MYDGF and attribute function to a set of residues conserved in MYDGFs but not the vanin base domain, which has a similar fold.

    • Valeriu Bortnov
    • , Marco Tonelli
    • , Woonghee Lee
    • , Ziqing Lin
    • , Douglas S. Annis
    • , Omar N. Demerdash
    • , Alex Bateman
    • , Julie C. Mitchell
    • , Ying Ge
    • , John L. Markley
    •  & Deane F. Mosher
  • Article
    | Open Access

    Here, Bhattacharya et al. chemically mutagenize Leishmania and identify genes associated with resistance to miltefosine and paromomycin by next generation sequencing. The study shows that a protein kinase (CDPK1) can mediate resistance to paromomycin by affecting translation.

    • Arijit Bhattacharya
    • , Philippe Leprohon
    • , Sophia Bigot
    • , Prasad Kottayil Padmanabhan
    • , Angana Mukherjee
    • , Gaétan Roy
    • , Hélène Gingras
    • , Anais Mestdagh
    • , Barbara Papadopoulou
    •  & Marc Ouellette

Health sciences

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  • Article
    | Open Access

    Polymorphisms in LMO1 are associated with increased susceptibility to develop neuroblastoma. Here, the authors show that LMO1 directly induces the transcription factor ASCL1, which regulates the differentiation of neurons, demonstrating that ASCL1 is part of the adrenergic neuroblastoma core regulatory circuit.

    • Lu Wang
    • , Tze King Tan
    • , Adam D. Durbin
    • , Mark W. Zimmerman
    • , Brian J. Abraham
    • , Shi Hao Tan
    • , Phuong Cao Thi Ngoc
    • , Nina Weichert-Leahey
    • , Koshi Akahane
    • , Lee N. Lawton
    • , Jo Lynne Rokita
    • , John M. Maris
    • , Richard A. Young
    • , A. Thomas Look
    •  & Takaomi Sanda
  • Article
    | Open Access

    Here, Bhattacharya et al. chemically mutagenize Leishmania and identify genes associated with resistance to miltefosine and paromomycin by next generation sequencing. The study shows that a protein kinase (CDPK1) can mediate resistance to paromomycin by affecting translation.

    • Arijit Bhattacharya
    • , Philippe Leprohon
    • , Sophia Bigot
    • , Prasad Kottayil Padmanabhan
    • , Angana Mukherjee
    • , Gaétan Roy
    • , Hélène Gingras
    • , Anais Mestdagh
    • , Barbara Papadopoulou
    •  & Marc Ouellette
  • Article
    | Open Access

    Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies.

    • Cody S. Nelson
    • , Kelsey M. Sumner
    • , Elizabeth Freedman
    • , Joseph W. Saelens
    • , Andrew A. Obala
    • , Judith N. Mangeni
    • , Steve M. Taylor
    •  & Wendy P. O’Meara

News & Comment

  • Editorial
    | Open Access

    The amplified warming of the Arctic in recent decades has been related to extreme weather events over the mid-latitudes, but its relative importance compared to other influences is not yet well understood. A Nature Research collection highlights evidence from theoretical and observational studies, as well as implications for future extreme events.

  • Comment
    | Open Access

    The European Space Agency (ESA) recently selected Comet Interceptor as its first ‘fast’ (F-class) mission. It will be developed rapidly to share a launch with another mission and is unique, as it will wait in space for a yet-to-be-discovered comet.

    • Colin Snodgrass
    •  & Geraint H Jones
  • Comment
    | Open Access

    As climate change thaws the Arctic’s foundations, new subterranean waterways form and threaten to wash away and decompose carbon once locked in permafrost. In this Comment, Vonk and co-authors outline a cross-disciplinary strategy--with hydrology at the forefront--to better understand the fate of Arctic carbon.

    • J. E. Vonk
    • , S. E. Tank
    •  & M. A. Walvoord
  • Q&A
    | Open Access

    Professor Marie Edmonds is a volcanologist at the University of Cambridge. She is interested in the role of magmatic volatiles in magma genesis, volcanic eruptions, and volatile geochemical cycling. Dr. Robert Hazen is a geologist at Carnegie Science and executive director of the Deep Carbon Observatory. His latest research has focused on the co-evolution of the geospheres and biospheres, and mineral diversity and distribution. Marie and Robert apply their research to help understand the chemical and biological roles of carbon in Earth.

  • Q&A
    | Open Access

    Dmitri Strukov (an electrical engineer, University of California at Santa Barbara), Giacomo Indiveri (an electrical engineer, University of Zurich), Julie Grollier (a material physicist, Unite Mixte de Physique CNRS) and Stefano Fusi (a neuroscientist, Columbia University) talked to Nature Communications about the opportunities and challenges in developing brain-inspired computing technologies, namely neuromorphic computing, and advocated effective collaborations crossing multidisciplinary research areas to support this emerging community.

  • Comment
    | Open Access

    Plastic pollution is a purely anthropogenic problem and cannot be solved without large-scale human action. Motivating mitigation actions requires more realistic assumptions about human decision-making based on empirical evidence from the behavioural sciences enabling the design of more effective interventions.

    • Lili Jia
    • , Steve Evans
    •  & Sander van der Linden

Focus

Energy Materials

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Energy Materials

Editors' Highlights: Each month our editors select a small number of Articles recently published in Nature Communications that they believe are particularly interesting or important.

Prateek Dongare, Benjamin Martindale, Adam Weingarten and Yaoqing Zhang

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