Archive: Clinical medicine
Clinical medicine 2008 Research Highlights
Infectious disease: An emerging threat
Felix Cheung
Published online: 03 December 2008 | doi:10.1038/nchina.2008.281
Original article citation:
et al. Nosocomial transmission of human granulocytic anaplasmosis in China. J. Am. Med. Assoc. 300, 2263–2270 (2008).
Top of pagePregnancy studies: Every little helps
Felix Cheung
Published online: 03 December 2008 | doi:10.1038/nchina.2008.282
Original article citation:
et al. Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: Double blind cluster randomised controlled trial. Br. Med. J. 337, a2001 (2008).
Top of pageImmunology: Alternate infection
Jane Qiu
Published online: 19 November 2008 | doi:10.1038/nchina.2008.270
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et al. Assessment of specific antibodies to F protein in serum samples from Chinese hepatitis C patients treated with interferon plus ribavarin. J. Clin. Microbiol. 46, 3746–3751 (2008).
Top of pageIntensive care medicine: Before pulling the tube
Felix Cheung
Published online: 12 November 2008 | doi:10.1038/nchina.2008.264
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et al. Prophylactic administration of parenteral steroids for preventing airway complications after extubation in adults: Meta-analysis of randomised placebo controlled trials. Br. Med. J. 337, a1841 (2008).
Top of pageMicroRNAs: Cancer 'fingerprints' this content is Open !
Jasmine Farsarakis
Published online: 29 October 2008 | doi:10.1038/nchina.2008.251
Original article citation:
et al. Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 18, 997–1006 (2008).
Top of pageFace transplantation: Another case of success
Jane Qiu
Published online: 10 September 2008 | doi:10.1038/nchina.2008.210
Original article citation:
et al. Human facial allotransplantation: A 2-year follow-up study. Lancet 372, 631–638 (2008).
Top of pageHIV treatment: In retrospect
Felix Cheung
Published online: 03 September 2008 | doi:10.1038/nchina.2008.204
Original article citation:
et al. The effect of highly active antiretroviral therapy on mortality among HIV-infected former plasma donors in China. Clin. Inf. Dis. 47, 825–833 (2008).
Top of pageMetabolic syndrome: Nonpeptide peps up therapy
Jane Qiu
Published online: 27 August 2008 | doi:10.1038/nchina.2008.199
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et al. Boc5, a non-peptidic glucagon-like peptide-1 receptor agonist, invokes sustained glycemic control and weight loss in diabetic mice. PLoS One 3, e2892 (2008).
Top of pageHepatitis B: Vaccination in full force
John Fox
Published online: 20 August 2008 | doi:10.1038/nchina.2008.195
Original article citation:
et al. A randomized controlled Phase IIb trial of antigen-antibody immunogenic complex therapeutic vaccine in chronic hepatitis B patients. PLoS One 3, e2565 (2008).
Top of pageCancer gene therapy: One stone, two birds
Jasmine Farsarakis
Published online: 30 July 2008 | doi:10.1038/nchina.2008.174
Original article citation:
et al. Adenovirus-mediated HCCS1 overexpression elicits a potent antitumor efficacy on human colorectal cancer and hepatoma cells both in vitro and in vivo. Cancer Gene Ther. doi: 10.1038/cgt.2008.52 (2008).
Top of pageLung cancer: Micro markers
Jasmine Farsarakis
Published online: 23 July 2008 | doi:10.1038/nchina.2008.167
Original article citation:
et al. Genetic variants of miRNA sequences and non-small cell lung cancer survival. J. Clin. Invest. 118, 2600–2608 (2008).
Top of pageLung disease: Breathing better
Felix Cheung
Published online: 25 June 2008 | doi:10.1038/nchina.2008.143
Original article citation:
et al. Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE study): A randomised placebo-controlled study. Lancet 371, 2013–2018 (2008).
Top of pageAtrial fibrillation: Back in the rhythm this content is Open !
Felix Cheung
Published online: 11 June 2008 | doi:10.1038/nchina.2008.133
Original article citation:
et al. Acacetin, a natural flavone, selectively inhibits human atrial repolarization potassium currents and prevents atrial fibrillation in dogs. Circulation 117, 2449–2457 (2008).
Top of pageStrokes: An alternative to aspirin this content is Open !
Felix Cheung
Published online: 04 June 2008 | doi:10.1038/nchina.2008.128
Original article citation:
et al. Cilostazol as an alternative to aspirin after ischaemic stroke: A randomised, double-blind, pilot study. Lancet Neurol. 7, 494–499 (2008).
Top of pageNephrotic syndrome: A blood-clot warning
Felix Cheung
Published online: 28 May 2008 | doi:10.1038/nchina.2008.119
Original article citation:
Portal vein thrombosis as the first sign of nephrotic syndrome. Nature Clin. Pract. Nephrol. doi: 10.1038/ncpneph0810 (2008).
Top of pageEpidemiology: Moderation in all things
Jane Qiu
Published online: 28 May 2008 | doi:10.1038/nchina.2008.122
Original article citation:
et al. Is exercise protective against influenza-associated mortality? PLoS One doi: 10.1371/journal.pone.0002108 (2008).
Top of pageAIDS treatment: The winning count
Felix Cheung
Published online: 21 May 2008 | doi:10.1038/nchina.2008.114
Original article citation:
et al. Association between V
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2V
2 T cells and disease progression after infection with closely related strains of HIV in China. Clin. Inf. Dis. 46, 1466–1472 (2008).Malaria: A new vaccine
John Fox
Published online: 14 May 2008 | doi:10.1038/nchina.2008.108
Original article citation:
et al. Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in Montanide ISA 720 in healthy adults. PLoS One 3, e1952 (2008).
Top of pageProstate cancer: Counter measures
Jane Qiu
Published online: 07 May 2008 | doi:10.1038/nchina.2008.101
Original article citation:
et al. Discovery and biological characterization of a novel series of androgen receptor modulators. Br. J. Pharmcol. doi: 10.1038/bjp.2008.107 (2008).
Top of pageAvian influenza: Evidence of human-to-human transmission
Felix Cheung
Published online: 23 April 2008 | doi:10.1038/nchina.2008.88
Original article citation:
et al. Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet doi: 10.1016/S0140-6736(08)60493-6 (2008).
Top of pageCarbon nanotubes: Body build-up
Felix Cheung
Published online: 09 April 2008 | doi:10.1038/nchina.2008.76
Original article citation:
et al. Biodistribution of pristine single-walled carbon nanotubes in vivo. J. Phys. Chem. C 111, 17761–17764 (2007).
Top of pageDiabetes: A bittersweet treatment this content is Open !
Felix Cheung
Published online: 09 April 2008 | doi:10.1038/nchina.2008.78
Original article citation:
et al. Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway. Chem. Biol. 15, 263–273 (2008).
Top of pageTraditional Chinese medicine: Ancient formula in modern times this content is Open !
Felix Cheung
Published online: 26 March 2008 | doi:10.1038/nchina.2008.64
Original article citation:
et al. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. PNAS 105, 4826–4831 (2008).
Top of pageNutrition: How eating vegetables can be bad for you this content is Open !
Felix Cheung
Published online: 19 March 2008 | doi:10.1038/nchina.2008.58
Original article citation:
et al. Vegetable-rich food pattern is related to obesity in China. Int. J. Obes. doi: 10.1038/ijo.2008.21 (2008).
Top of pageLiver cancer: A marker of disease
Jasmine Farsarakis
Published online: 19 March 2008 | doi:10.1038/nchina.2008.59
Original article citation:
et al. Significance of CD90+ cancer stem cells in human liver cancer. Cancer Cell 13, 153–166 (2008).
Top of pageEarly pregnancy: Cellular interactions in the placenta
Jasmine Farsarakis
Published online: 05 March 2008 | doi:10.1038/nchina.2008.51
Original article citation:
Human trophoblasts recruited T lymphocytes and monocytes into decidua by secretion of chemokine CXCL16 and interaction with CXCR6 in the first-trimester pregnancy. J. Immunol. 180, 2367–2375 (2008).
Top of pageHypertension: Guilty SNPs exposed
Jasmine Farsarakis
Published online: 20 February 2008 | doi:10.1038/nchina.2008.38
Original article citation:
et al. Single-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study. J. Human Hypertension 22, 151–153 (2008).
Top of pageChemotherapy: Improved packaging, improved performance
Jasmine Farsarakis
Published online: 06 February 2008 | doi:10.1038/nchina.2008.25
Original article citation:
et al. Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin. J. Natl Cancer Inst. 99, 1004–1015 (2007).
Top of pageInfluenza surveillance: Seasonal predictors
John Fox
Published online: 30 January 2008 | doi:10.1038/nchina.2008.19
Original article citation:
et al. Synchrony of clinical and laboratory surveillance for influenza in Hong Kong. PLoS ONE 3, e1399 (2008).
Top of pageAntipsychotic medication: Managing weight gain
Jasmine Farsarakis
Published online: 30 January 2008 | doi:10.1038/nchina.2008.22
Original article citation:
et al. Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain. JAMA 299, 185–193 (2008).
Top of pageParkinson's disease: Green tea protection
John Fox
Published online: 10 January 2008 | doi:10.1038/nchina.2008.3
Original article citation:
et al. Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway. Biol. Psychiatry 62, 1353–1362 (2007).
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