Archive: Biotechnology
Biotechnology 2009 Research Highlights
Stem cells: Skin treatment for your liver
Felix Cheung
Published online: 30 September 2009 | doi:10.1038/nchina.2009.188
Original article citation:
et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res. doi:10.1038/cr.2009.107 (2009)
Top of pageGenomics: Silkworm secrets this content is Open !
Felix Cheung
Published online: 16 September 2009 | doi:10.1038/nchina.2009.183
Original article citation:
et al. Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science doi:10.1126/science.1176620 (2009).
Top of pageBiological materials: A tooth for a tooth
Felix Cheung
Published online: 09 September 2009 | doi:10.1038/nchina.2009.178
Original article citation:
, , & Chemical regeneration of human tooth enamel under near-physiological conditions. Chem. Commun. doi:10.1039/b911407f (2009).
Top of pageCardiology: Heart therapy this content is Open !
Felix Cheung
Published online: 02 September 2009 | doi:10.1038/nchina.2009.174
Original article citation:
et al. Increased expression of integrin-linked kinase attenuates left ventricular remodeling and improves cardiac function after myocardial infarction. Circulation doi:10.1161/CIRCULATIONAHA.109.870725 (2009).
Top of pageStem cells: Full pluripotency this content is Open !
Felix Cheung
Published online: 12 August 2009 | doi:10.1038/nchina.2009.160
Original article citation:
, , , & iPS cells can support full-term development of tetraploid blastocyst-complemented embryos. Cell Stem Cell doi:10.1016/j.stem.2009.07.001 (2009).
Top of pageStem cells: True pluripotency this content is Open !
Felix Cheung
Published online: 24 July 2009 | doi:10.1038/nchina.2009.155
Original article citation:
et al. iPS cells produce viable mice through tetraploid complementation. Nature doi:10.1038/nature08267 (2009).
Top of pageNanobiotechnology: 'Penicillin' for the brain this content is Open !
Felix Cheung
Published online: 08 July 2009 | doi:10.1038/nchina.2009.139
Original article citation:
et al. Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent. Nature Nanotechnol. doi:10.1038/nnano.2009.153 (2009).
Top of pageStructural biology: The amino acid antiporter
Felix Cheung
Published online: 24 June 2009 | doi:10.1038/nchina.2009.131
Original article citation:
et al. Structure and mechanism of an amino acid antiporter. Science doi:10.1126/science.1173654 (2009).
Top of pageMetabolism: Goose liver tells a big fat story
Felix Cheung
Published online: 27 May 2009 | doi:10.1038/nchina.2009.115
Original article citation:
et al. The role of insulin and glucose in goose primary hepatocyte triglyceride accumulation. J. Exp. Biol. 212, 1553–1558 (2009).
Top of pageStem cells: This little piggy joined the pluripotency list
Felix Cheung
Published online: 20 May 2009 | doi:10.1038/nchina.2009.111
Original article citation:
et al. Generation of induced pluripotent stem cell lines from Tibetan miniature pig. J. Biol. Chem. doi:10.1074/jbc.M109.008938 (2009).
Top of pageSurface chemistry: Sticky business
Felix Cheung
Published online: 20 May 2009 | doi:10.1038/nchina.2009.112
Original article citation:
, & Using azobenzene-embedded self-assembled monolayers to photochemically control cell adhesion reversibly. Angew. Chem. Int. Ed. doi:10.1002/anie.200901130 (2009).
Top of pageApoptosis: Negative regulator exposed
Felix Cheung
Published online: 29 April 2009 | doi:10.1038/nchina.2009.85
Original article citation:
et al. KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis. Nature Cell Biol. doi:10.1038/ncb1864 (2009).
Top of pageNanosensors: A sheep in wolf's clothing this content is Open !
Ai Lin Chun
Published online: 29 April 2009 | doi:10.1038/nchina.2009.89
Original article citation:
et al. Imaging viral behavior in mammalian cells with self-assembled capsid–quantum-dot hybrid particles. Small 5, 718–726 (2009).
Top of pageStem cells: Cracking the egg's potential this content is Open !
Felix Cheung
Published online: 22 April 2009 | doi:10.1038/nchina.2009.79
Original article citation:
et al. Production of offspring from a germline stem cell line derived from neonatal ovaries. Nature Cell Biol. doi:10.1038/ncb1869 (2009).
Top of pageBiological materials: Release, repair and regenerate
Felix Cheung
Published online: 08 April 2009 | doi:10.1038/nchina.2009.67
Original article citation:
et al. Designed amphiphilic peptide forms stable nanoweb, slowly releases encapsulated hydrophobic drug, and accelerates animal hemostasis. Proc. Natl Acad. Sci. USA doi:10.1073/pnas.0900026106 (2009).
Top of pageAnalytical chemistry: Turning a new page
Felix Cheung
Published online: 01 April 2009 | doi:10.1038/nchina.2009.62
Original article citation:
et al. Novel application of carbon nanotubes for improving resolution in detecting human serum proteins with native polyacrylamide gel electrophoresis. Nano Lett. doi:10.1021/nl802935s (2009).
Top of pageRice genetics: Know grain, know gain this content is Open !
Felix Cheung
Published online: 01 April 2009 | doi:10.1038/nchina.2009.64
Original article citation:
et al. Natural variation at the DEP1 locus enhances grain yield in rice. Nature Genet. doi:10.1038/ng.352 (2009).
Top of pageGenomics: A fishing exercise
Jane Qiu
Published online: 25 March 2009 | doi:10.1038/nchina.2009.55
Original article citation:
et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. doi:10.1101/gr.086595.108 (2009).
Top of pageMicroRNA detection: Spot the difference
Tim Reid
Published online: 18 March 2009 | doi:10.1038/nchina.2009.49
Original article citation:
et al. Highly sensitive determination of microRNA using target-primed and branched rolling-circle amplification. Angew. Chem. Int. Ed. doi:10.1002/anie.200805665 (2009).
Top of pageNanomaterials: Penetrating plants this content is Open !
Tim Reid
Published online: 04 March 2009 | doi:10.1038/nchina.2009.39
Original article citation:
et al. Carbon nanotubes as molecular transporters for walled plant cells. Nano Lett. doi:10.1021/nl803083u (2009).
Top of pageOncology: Cancer connection
Felix Cheung
Published online: 25 February 2009 | doi:10.1038/nchina.2009.31
Original article citation:
et al. Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers. Oncogene doi:10.1038/onc.2008.503 (2009).
Top of pageChemical biology: On neutral ground
Felix Cheung
Published online: 18 February 2009 | doi:10.1038/nchina.2009.27
Original article citation:
et al. A near-infrared neutral pH fluorescent probe for monitoring minor pH changes: Imaging in living HepG2 and HL-7702 cells. J. Am. Chem. Soc. doi:10.1021/ja809149g (2009).
Top of pageStem cells: Rat cells reprogrammed
Jane Qiu
Published online: 11 February 2009 | doi:10.1038/nchina.2009.19
Original article citation:
et al. Generation of induced pluripotent stem cell lines from adult rat cells. Cell Stem Cell 4, 11–15 (2009).
Top of pageNanodevices: Triangle tricks
Tim Reid
Published online: 04 February 2009 | doi:10.1038/nchina.2009.17
Original article citation:
et al. A pH-driven, reconfigurable DNA nanotriangle. Chem. Commun. doi:10.1039/b813064g (2009).
Top of pageStem cell: Monkey business
Jane Qiu
Published online: 07 January 2009 | doi:10.1038/nchina.2008.299
Original article citation:
et al. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Cell Stem Cells 3, 587–590 (2008).
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