Epistatic maps are used to delineate the modes of interaction of genes in various cellular pathways. A new epistatic map of nearly 400 genes involved in plasma membrane biology has revealed unexpected modes of regulation of endocytosis and sphingolipid metabolism.
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Futerman, A., Schuldiner, M. The plasma membrane code. Nat Chem Biol 6, 487–488 (2010). https://doi.org/10.1038/nchembio.397
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DOI: https://doi.org/10.1038/nchembio.397
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