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Commentary

Nature Chemical Biology 5, 521–525 (1 August 2009) | doi:10.1038/nchembio0809-521

Missing in action: enzyme functional annotations in biological databases

Nicholas Furnham , John S Garavelli , Rolf Apweiler & Janet M Thornton

Automatically assigning function to a gene product remains a challenging task to perform accurately. Unfortunately, the lack of high-throughput experimental pipelines to reveal biological function results in a chronic lack of validated data.