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Nature Chemical Biology 5, 452–453 (1 July 2009) | doi:10.1038/nchembio0709-452
Encoding chemistry
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Abstract
The isolation of molecules that bind tightly and specifically to proteins of interest is a central challenge in chemistry, biology and the pharmaceutical sciences. So far, monoclonal antibodies still represent the only class of molecules for which specific, high-affinity binders can be rapidly isolated against virtually any conceivable target protein.
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