News and Views
Nature Chemical Biology 5, 376 - 377 (2009)
doi:10.1038/nchembio0609-376
Pulling out the coordination mechanism of myosin-VI
Martin Lindén1
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Martin Lindén is in the Department of Environmental Science, Policy and Management, University of California, Berkeley California, USA.
e-mail: linden@nature.berkeley.edu
Abstract
Efficient transport by single two-headed motor proteins requires coordination of the motor domains. A new single-molecule study sheds light on an important coordination mechanism by demonstrating an asymmetric strain dependence of the weak-to-strong binding transition in myosin-VI heads.
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