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Nature Chemical Biology 5, 80–81 (1 February 2009) | doi:10.1038/nchembio0209-80

Research highlights

Decoding ERAD glycans Misfolded proteins are cleared from the endoplasmic reticulum in a process called ER-associated degradation (ERAD). Recognition of ERAD substrates depends on the presence of both misfolded regions and specific N-linked glycans, but many of the molecular details of this process are unknown.