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Nature Chemical Biology 4, 524 - 525 (2008)
doi:10.1038/nchembio0908-524
From yeast to alkaloids
Jay Keasling1
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Jay Keasling is in the Departments of Chemical Engineering and Bioengineering, University of California, Berkeley, California 94720, USA The Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA, and the Joint BioEnergy Institute, 5885 Hollis, Emeryville, California 94608, USA.
e-mail: keasling@berkeley.edu
Abstract
Alkaloids, which include caffeine and morphine, are a large class of pharmacologically active plant compounds that are often difficult to chemically synthesize. Incorporation of benzylisoquinoline alkaloid pathways in yeast will facilitate the production of natural and non-natural alkaloids.
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