The zebrafish has provided insights into the mechanisms of vertebrate development, in large part due to its amenability to optical imaging. While fluorescent proteins and other genetically encoded reporters are valuable imaging tools, synthetic probes can reveal dynamical processes such as glycan biosynthesis that are undetectable by conventional methods.
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References
Danielian, P.S., Muccino, D., Rowitch, D.H., Michael, S.K. & McMahon, A.P. Curr. Biol. 8, 1323–1326 (1998).
Long, Q. et al. Development 124, 4105–4111 (1997).
Laughlin, S.T., Baskin, J.M., Amacher, S.L. & Bertozzi, C.R. Science 320, 664–667 (2008).
Mahal, L.K., Yarema, K.J. & Bertozzi, C.R. Science 276, 1125–1128 (1997).
Rabuka, D., Hubbard, S.C., Laughlin, S.T., Argade, S.P. & Bertozzi, C.R. J. Am. Chem. Soc. 128, 12078–12079 (2006).
Vocadlo, D.J., Hang, H.C., Kim, E.J., Hanover, J.A. & Bertozzi, C.R. Proc. Natl. Acad. Sci. USA 100, 9116–9121 (2003).
Saxon, E. & Bertozzi, C.R. Science 287, 2007–2010 (2000).
Baskin, J.M. et al. Proc. Natl. Acad. Sci. USA 104, 16793–16797 (2007).
Haines, N. & Irvine, K.D. Nat. Rev. Mol. Cell Biol. 4, 786–797 (2003).
Princivalle, M. & de Agostini, A. Int. J. Dev. Biol. 46, 267–278 (2002).
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Chen, J. Fish 'n clicks. Nat Chem Biol 4, 391–392 (2008). https://doi.org/10.1038/nchembio0708-391
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DOI: https://doi.org/10.1038/nchembio0708-391
