News and Views
Nature Chemical Biology 4, 391 - 392 (2008)
doi:10.1038/nchembio0708-391
Fish 'n clicks
James K Chen1
- James K. Chen is at the Department of Chemical and Systems Biology, Stanford University School of Medicine, 269 Campus Drive, CCSR 3155, Stanford, California 94305-5174, USA. e-mail: jameschen@stanford.edu
Abstract
The zebrafish has provided insights into the mechanisms of vertebrate development, in large part due to its amenability to optical imaging. While fluorescent proteins and other genetically encoded reporters are valuable imaging tools, synthetic probes can reveal dynamical processes such as glycan biosynthesis that are undetectable by conventional methods.
