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Brief Communication

Nature Chemical Biology 4, 341–343 (1 June 2008) | doi:10.1038/nchembio.84

A global assembly line for cyanobactins

Mohamed S Donia , Jacques Ravel & Eric W Schmidt

More than 100 cyclic peptides harboring heterocyclized residues are known from marine ascidians, sponges and different genera of cyanobacteria. Here, we report an assembly line responsible for the biosynthesis of these diverse peptides, now called cyanobactins, both in symbiotic and free-living cyanobacteria.