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Nature Chemical Biology 4, v (1 April 2008) | doi:10.1038/nchembio0408-v

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Antimalarial antibodies Glycosylphosphatidylinositol (GPI) accounts for as much as 90% of protein glycosylation in protozoan parasites and is an important malarial toxin. Anti-GPI antibodies are found in the sera of individuals in regions with endemic malaria, and recent studies with a rodent model have suggested that GPI-based vaccines may be protective against malaria.