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Nature Chemical Biology 4, 158 - 159 (2008)
doi:10.1038/nchembio0308-158
Delivery of tailor-made cobalamin to methylmalonyl-CoA mutase
Vahe Bandarian1
- Vahe Bandarian is in the Department of Biochemistry and Molecular Biophysics, 1041 East Lowell Street, Tucson, Arizona 85721, USA. e-mail: vahe@email.arizona.edu
Abstract
Methylmalonyl coenzyme A mutase (MCM) catalyzes the adenosylcobalamin-dependent isomerization of methylmalonyl-CoA to succinyl-CoA. Adenosyltransferase, an enzyme that carries out the final step in biosynthesis of adenosylcobalamin, is shown to be involved in delivery of the cofactor to MCM.
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RESEARCH
Adenosyltransferase tailors and delivers coenzyme B 12Nature Chemical Biology Brief Communication (01 Mar 2008)
