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Nature Chemical Biology 4, 90–91 (1 February 2008) | doi:10.1038/nchembio0208-90
Unexpected tails of a Ca2+ sensor
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Abstract
The neuronal calcium sensor (NCS) protein family of small calcium-binding proteins are emerging as multifaceted regulators of numerous cell signaling events. NCS proteins can be distinguished from their more ubiquitously expressed and distantly related cousin calmodulin by key features such as their often exquisitely high affinity for Ca2+, their specific tissue and cellular distributions and their unique subcellular localizations.
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