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Acting together, bacterial clusters initiate coagulation

Bacterial infections have long been associated with coagulation, but the mechanism is not well understood. New insights into bacterial spatial localization are shedding light on how bacterial clusters can trigger coagulation in a process known as 'quorum acting'.

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Figure 1: Coagulation induced by the presence of bacteria is governed by spatial localization, or clustering, rather than by the total concentration of a bacterial species in the blood.

Katie Ris-Vicari

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Borenstein, J. Acting together, bacterial clusters initiate coagulation. Nat Chem Biol 4, 718–719 (2008). https://doi.org/10.1038/nchembio1208-718

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