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Nature Chemical Biology 4, 650–651 (1 November 2008) | doi:10.1038/nchembio1108-650

To dislodge an enzyme from an ion channel, try steroids

Susy C Kohout & Ehud Y Isacoff

How many things can one protein do, and how do you make it stop? For a class of auxiliary subunits of a K+ channel, Kvβs, the answers are “many” and “steroids”. Kv1 channels shape neuronal action potentials and regulate lymphocytes.