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Nature Chemical Biology 4, 586 - 587 (2008)
doi:10.1038/nchembio1008-586

Sugars stack up

Chad Tatko1

  1. Chad Tatko is in the Department of Chemistry and Biochemistry, Calvin College, 3201 Burton Street, Grand Rapids, Michigan 49546, USA.
    e-mail: cdt2@calvin.edu


Sugar binding by a variety of biomolecules is generally assumed to rely on hydrogen bonding and ionic interactions. A new study shows that arene-carbohydrate interactions are enthalpically driven through nontraditional C-Hdotdotdotpi type hydrogen bonds.

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