News and Views
Nature Chemical Biology 4, 586 - 587 (2008)
doi:10.1038/nchembio1008-586
Sugars stack up
Chad Tatko1
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Chad Tatko is in the Department of Chemistry and Biochemistry, Calvin College, 3201 Burton Street, Grand Rapids, Michigan 49546, USA.
e-mail: cdt2@calvin.edu
Abstract
Sugar binding by a variety of biomolecules is generally assumed to rely on hydrogen bonding and ionic interactions. A new study shows that arene-carbohydrate interactions are enthalpically driven through nontraditional C-H


type hydrogen bonds.

