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Nature Chemical Biology 4, 19–20 (1 January 2008) | doi:10.1038/nchembio0108-19

Chemical |[ldquo]|knockout|[rdquo]| challenges the amphotericin B channel model

Sergey A Kozmin

Membrane channels regulate the flow of substances in and out of the cell and are typically self-assembled from multiple protein subunits inside the lipid bilayer. However, a very few small molecules are also capable of exerting this highly sophisticated function.