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Letter
Nature Chemical Biology 3, 492–497 (1 August 2007) | doi:10.1038/nchembio.2007.13
A new thiamin salvage pathway
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Abstract
The physiological function for thiaminase II, a thiamin-degrading enzyme, has eluded investigators for more than 50 years. Here, we demonstrate that this enzyme is involved in the regeneration of the thiamin pyrimidine rather than in thiamin degradation, and we identify a new pathway involved in the salvage of base-degraded forms of thiamin.
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