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Nature Chemical Biology 3, 455 - 457 (2007)
doi:10.1038/nchembio0807-455
Chaperoning cell death: a critical dual role for Hsp90 in small-cell lung cancer
Paul Workman1 & Marissa V Powers1
- Paul Workman and Marissa V. Powers are in the Cancer Research UK Centre for Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK. e-mail: paul.workman@icr.ac.uk
Abstract
Chemical probes reveal Hsp90 to be a key molecule for the control of apoptosis in small-cell lung cancer—with important implications for Hsp90 biology and cancer treatment.
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