News and Views
Nature Chemical Biology 3, 454 - 455 (2007)
doi:10.1038/nchembio0807-454
At the crossroad of thiamine degradation and biosynthesis
Lucien Bettendorff1
- Lucien Bettendorff is at the Center for Cellular and Molecular Neurobiology, University of Liège, Building B36, 1, avenue de l'Hôpital, B-4000 Liège, Belgium. e-mail: l.bettendorff@ulg.ac.be
Abstract
The physiological significance of thiaminase II has escaped our understanding for many years. The recent discovery of a new thiamine salvage pathway shows that this enzyme is involved in the regeneration of precursors for thiamine biosynthesis.
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