Supplementary information
From the following article
Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor
William W Ja, Anthony P West, Jr, Silvia L Delker, Pamela J Bjorkman, Seymour Benzer & Richard W Roberts
Nature Chemical Biology 3, 415 - 419 (2007) Published online: 3 June 2007
doi:10.1038/nchembio.2007.2
Supplementary Fig. 1
Selected peptides recognize the full-length Methuselah receptor.
Supplementary Fig. 2
Amino acid analysis of selected peptides.
Supplementary Fig. 3
Peptide binding site is not localized to Methuselah Trp120.
Supplementary Fig. 4
Expression of R8-12 extends Drosophila lifespan.
Supplementary Fig. 5
Binding analysis of R8-04 to Methuselah by surface plasmon resonance.
Supplementary Table 1
Selected peptide sequences from Methuselah selection.
Supplementary Table 2
Crystallography data collection and refinement statistics.
Supplementary Methods
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