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Nature Chemical Biology 3, 307 - 309 (2007)
doi:10.1038/nchembio0607-307
A sugar-coated switch for cellular growth and arrest
Naoyuki Taniguchi1
- Naoyuki Taniguchi is in the Department of Disease Glycomics, Institute for Microbial Diseases, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. e-mail: tani52@wd5.so-net.ne.jp
Abstract
The reversible attachment of an activated form of N-acetylglucosamine (UDP-GlcNAc) acts as a molecular switch between the growth and arrest of cells, establishing a new role for cell surface glycans.
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