1. Anne Simonsen and Harald Stenmark are in the Centre for Cancer Biomedicine, University of Oslo, and the Department of Biochemistry, the Norwegian Radium Hospital, Montebello, N-0310 Oslo, Norway. e-mail: stenmark@ulrik.uio.no

Abstract

New inducers of autophagy—the process by which cells use lysosomes to degrade portions of their cytoplasm—are lead compounds for new drugs targeting neurodegenerative protein aggregation diseases.

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