News and Views


Nature Chemical Biology 3, 206 - 207 (2007)
doi:10.1038/nchembio0407-206

Iron-sulfur clusters as oxygen-responsive molecular switches

F Wayne Outten1

  1. F. Wayne Outten is in the Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, SC 29208, USA. e-mail: wayne.outten@chem.sc.edu


FNR is a global regulator of the Escherichia coli aerobic-anaerobic growth transition and relies on an [Fe-S] cluster cofactor to control its oxygen-dependent activity. Details of the chemical reaction of oxygen with the [Fe-S] cluster reveal how this cofactor is used for oxygen sensing.

Top


MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated.

NEWS AND VIEWS

Cancer A radical approach to treatment

Nature News and Views (21 Sep 2000)


Extra navigation

Subscribe to Nature Chemical Biology

Subscribe

Search PubMed for

Open Innovation Challenges

naturejobs