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Nature Chemical Biology 3, v (1 March 2007) | doi:10.1038/nchembio0307-v

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A click of the RSK Because of the functional redundancy built into the MEK-ERK signal transduction pathway, it has been difficult to develop specific inhibitors for individual kinases in this cascade. Cohen et al. have now done just that for the p90 ribosomal S6 kinases RSK1 and RSK2.