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Nature Chemical Biology 3, 20–21 (1 January 2007) | doi:10.1038/nchembio0107-20

Sensing RNA virus infections

Christopher F Basler & Adolfo Garc|[iacute]|a-Sastre

The innate immune response must be regulated to prevent its inadvertent activation while allowing it to quickly respond to pathogenic organisms. Thus, mechanisms have evolved to allow its triggering by motifs common to important pathogens.