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Nature Chemical Biology 3, 19 - 20 (2007)
doi:10.1038/nchembio0107-19
Are we there yet?
William C Merrick1
- William C. Merrick is in the Department of Biochemistry, Case Western Reserve University, 100900 Euclid Avenue, Cleveland, Ohio 44106-4935, USA. e-mail: wcm2@case.edu
Abstract
After years of waiting, the road map for the path of the mRNA on the ribosome with its associated tRNAs has been completed. In contrast to the amino-acid-coding nucleotides of the body of the mRNA, the Shine-Delgarno region appears to take an unexpected turn on the surface of the 30S subunit in the transition from the initiation complex to the postinitiation complex.
