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Nature Chemical Biology 2, 455 - 456 (2006)
doi:10.1038/nchembio0906-455

One-way traffic control in replication termination

Karsten Theis1

  1. Karsten Theis is in the Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, Massachusetts 01002, USA. e-mail: theis@biochem.umass.edu


Tus proteins bound to multiple ter sequences on DNA determine the site of DNA replication termination in Escherichia coli. Biochemical and structural studies reveal how the Tus–ter complex arrests replication forks in a direction-sensitive manner.

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