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Nature Chemical Biology 2, 453 - 455 (2006)
doi:10.1038/nchembio0906-453
Charging the batteries to heal wounds through PI3K
Bart Vanhaesebroeck1
- Bart Vanhaesebroeck is at the Ludwig Institute for Cancer Research, 91 Riding House Streeet, London W1W 7BS, UK and the Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK. e-mail: bartvanh@ludwig.ucl.ac.uk
Abstract
Endogenous electric fields in wounds have been documented for centuries, but they have received little attention from the scientific community. A new study shows that manipulation of these electric fields affects wound healing in vivo and identifies the phosphoinositide 3-kinase signaling pathway as a key component of cell migration in response to electric cues.
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RESEARCH
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTENNature Letters to Editor (27 Jul 2006)
