Supplementary information

From the following article

A clinical drug library screen identifies astemizole as an antimalarial agent

Curtis R Chong, Xiaochun Chen, Lirong Shi, Jun O Liu & David J Sullivan, Jr

Nature Chemical Biology 2, 415 - 416 (2006) Published online: 2 July 2006

doi:10.1038/nchembio806

BACK TO ARTICLE

Supplementary Fig. 1

Comparison of The Johns Hopkins Clinical Compound Library with other libraries of existing drugs.

Supplementary Fig. 2

Selected screening results from drug classes of interest.

Supplementary Fig. 3

Astemizole reversibly inhibits heme crystallization and accumulates in the P. falciparum food vacuole.

Supplementary Table 1

Existing drugs that showed >50% inhibition of 3D7 proliferation at 10 muM.

BACK TO ARTICLE

DOWNLOAD BROWSER PLUGINS AND OTHER APPLICATIONS


Flash movies

Audio files

Chemical structures

Microarray

Compressed Stuff files

Compressed Zip files

Systems Biology Markup Language files (SBML)

Chemical Markup language files (CML)

BACK TO ARTICLE