Table 1

From the following article

A clinical drug library screen identifies astemizole as an antimalarial agent

Curtis R Chong, Xiaochun Chen, Lirong Shi, Jun O Liu & David J Sullivan, Jr

Nature Chemical Biology 2, 415 - 416 (2006) Published online: 2 July 2006

doi:10.1038/nchembio806

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Table 1. Astemizole inhibition of three P. falciparum strains of different chloroquine sensitivity

Figures, schemes and tables index
Plasmodium falciparum strainAstemizole IC50 (nM)Norastemizole IC50 (nM)Desmethylastemizole IC50 (nM)Chloroquine IC50 (nM)
3D7227 plusminus 6.44,477 plusminus 15117 plusminus 1.431.8 plusminus 3.5
Dd2457 plusminus 12.33,590 plusminus 16106.2 plusminus 10.379.3 plusminus 6.8
ItG734 plusminus 2.22,230 plusminus 93456.8 plusminus 27107.3 plusminus 13.8
Figures, schemes and tables index
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