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Nature Chemical Biology 2, 396 - 398 (2006)
doi:10.1038/nchembio0806-396
Lipid-induced phenotypes
Carsten Schultz1
- Carsten Schultz is in the Gene Expression Unit at the European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany. e-mail: schultz@embl.de
Abstract
Sphingosine 1-phosphate (S1P), a lysophospholipid and known immune regulator, stimulates distinct signaling pathways. A specific S1P antagonist that can be used systemically for the first time provides an indispensable tool for elucidating the therapeutic potential of the S1P signaling pathway.
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