Supplementary information

From the following article

Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway

Rebecca A Butcher, Bhupinder S Bhullar, Ethan O Perlstein, Gerald Marsischky, Joshua LaBaer & Stuart L Schreiber

Nature Chemical Biology 2, 103 - 109 (2006) Published online: 15 January 2006

doi:10.1038/nchembio762

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Supplementary Fig. 1

Analysis of amplification method.

Supplementary Fig. 2

Correlation plot for the two replicate microarray experiments of rapamycin treatment.

Supplementary Fig. 3

Wild-type yeast are hypersensitive to LY-83583 on non-fermentable carbon sources.

Supplementary Fig. 4

Inhibition of Guf1p GTPase activity by LY-83583.

Supplementary Table 1

Overexpression strains that showed resistance or hypersensitivity to rapamycin.

Supplementary Table 2

Complete data set.

Supplementary Table 3

Retesting of the rapamycin sensitivity of strains that were enriched or depleted after rapamycin treatment.

Supplementary Table 4

Retesting of the LY-83583 sensitivity of strains that were enriched or depleted after LY-83583 treatment.

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