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Letter

Nature Chemical Biology 2, 591–595 (1 November 2006) | doi:10.1038/nchembio820

An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus

Peng R Chen , Taeok Bae , Wade A Williams , Erica M Duguid , Phoebe A Rice , Olaf Schneewind & Chuan He

Staphylococcus aureus is a human pathogen responsible for most wound and hospital-acquired infections. The protein MgrA is both an important virulence determinant during infection and a regulator of antibiotic resistance in S.