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November 2006, Volume 2 Number 11 pp559-644

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In This Issue

In This Issue

 pv

doi:10.1038/nchembio1106-v

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Editorial

Membranes stay afloat

 p559

doi:10.1038/nchembio1106-559

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Commentaries

Phase behavior of lipid mixtures

 pp560 - 563

Gerald W Feigenson

doi:10.1038/nchembio1106-560

The physical chemistry of biological membranes

 pp564 - 567

Joshua Zimmerberg and Klaus Gawrisch

doi:10.1038/nchembio1106-564

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Elements

Randy Schekman

 p568

Mirella Bucci

doi:10.1038/nchembio1106-568

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News and Views

Right on cue

 pp569 - 570

Douglas A Lauffenburger

doi:10.1038/nchembio1106-569

See also: Article by Schlee et al.

S-nitrosylation TRiPs a calcium switch

 pp570 - 571

Matthew W Foster, Douglas T Hess and Jonathan S Stamler

doi:10.1038/nchembio1106-570

See also: Article by Yoshida et al.

Flip-flopping salt bridges gate an ion channel

 pp572 - 573

Anna Moroni and Gerhard Thiel

doi:10.1038/nchembio1106-572

See also: Article by Hong et al.

Solving an old puzzle in phospholipid biosynthesis

 pp573 - 574

Gustavo E Schujman and Diego de Mendoza

doi:10.1038/nchembio1106-573

Research Highlights

 p575

doi:10.1038/nchembio1106-575

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Perspective

Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid signaling

 pp576 - 583

Kristina E Ile, Gabriel Schaaf and Vytas A Bankaitis

Published online: 18 October 2006 | doi:10.1038/nchembio835

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Review

Trafficking and signaling by fatty-acylated and prenylated proteins

 pp584 - 590

Marilyn D Resh

Published online: 18 October 2006 | doi:10.1038/nchembio834

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Letter

An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus

 pp591 - 595

Peng R Chen, Taeok Bae, Wade A Williams, Erica M Duguid, Phoebe A Rice, Olaf Schneewind and Chuan He

Published online: 17 September 2006 | doi:10.1038/nchembio820

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Articles

Nitric oxide activates TRP channels by cysteine S-nitrosylation

 pp596 - 607

Takashi Yoshida, Ryuji Inoue, Takashi Morii, Nobuaki Takahashi, Shinichiro Yamamoto, Yuji Hara, Makoto Tominaga, Shunichi Shimizu, Yoji Sato and Yasuo Mori

Published online: 24 September 2006 | doi:10.1038/nchembio821

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Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance

 pp608 - 617

Campbell McInnes, Aveek Mazumdar, Mokdad Mezna, Christopher Meades, Carol Midgley, Fred Scaerou, Lee Carpenter, Mairi Mackenzie, Paul Taylor, Malcolm Walkinshaw, Peter M Fischer and David Glover

Published online: 08 October 2006 | doi:10.1038/nchembio825

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Probing cell-division phenotype space and Polo-like kinase function using small molecules

 pp618 - 626

Ulf Peters, Joseph Cherian, Jeffrey H Kim, Benjamin H Kwok and Tarun M Kapoor

Published online: 08 October 2006 | doi:10.1038/nchembio826

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Electrostatic couplings in OmpA ion-channel gating suggest a mechanism for pore opening

 pp627 - 635

Heedeok Hong, Gabor Szabo and Lukas K Tamm

Published online: 15 October 2006 | doi:10.1038/nchembio827

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Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret

 pp636 - 644

Sandra Schlee, Paul Carmillo and Adrian Whitty

Published online: 01 October 2006 | doi:10.1038/nchembio823

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