Supplementary information
From the following article
Structural basis for macrolactonization by the pikromycin thioesterase
David L Akey, Jeffrey D Kittendorf, John W Giraldes, Robert A Fecik, David H Sherman & Janet L Smith
Nature Chemical Biology 2, 537 - 542 (2006) Published online: 10 September 2006
doi:10.1038/nchembio824
Supplementary Fig. 1
Time course of Pik TE inactivation by reduced pentaketide 11.
Supplementary Fig. 2
Stereodiagram of simulated-annealing Fo – Fc omit maps.
Supplementary Table 1
Data collection and refinement statistics.
Supplementary Scheme 1
Synthesis of diphenylphosphonate pentaketide 11.
Supplementary Methods
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