Supplementary information : Analysis of drug-induced effect patterns to link structure and side effects of medicines : Nature Chemical Biology

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Analysis of drug-induced effect patterns to link structure and side effects of medicines

Anton F Fliri, William T Loging, Peter F Thadeio & Robert A Volkmann

Nature Chemical Biology 1, 389 - 397 (2005) Published online: 6 November 2005

doi:10.1038/nchembio747

Supplementary Fig. 1

The experimental design for investigating the information exchange between drug-induced protein network perturbations to drug-induced organ systems perturbations.

Supplementary Fig. 1 - Download PDF file (149KB)

Supplementary Fig. 2

Positions of ninety-two protein assays in the mammalian proteome network.

Supplementary Fig. 2 - Download PDF file (3,114KB)

Supplementary Fig. 3

Sedative-hypnotic cluster.

Supplementary Fig. 3 - Download PDF file (400KB)

Supplementary Fig. 4

Side effect distances compared to BioSpectra distances.

Supplementary Fig. 4 - Download PDF file (229KB)

Supplementary Table 1

List of ninety-two assays.

Supplementary Table 1 - Download PDF file (51KB)

Supplementary Table 2

List of 872 medicines.

Supplementary Table 2 - Download PDF file (49KB)

Supplementary Table 3

ADRS.

Supplementary Table 3 - Download PDF file (43KB)

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Supplementary information