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December 2005, Volume 1 Number 7 pp349-397

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In This Issue

In This Issue

 pv

doi:10.1038/nchembio1205-v

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Editorial

Coming clean

 p349

doi:10.1038/nchembio1205-349

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News and Views

Small molecules thwart crash and burn

 pp351 - 353

Samuel Sidi and A Thomas Look

doi:10.1038/nchembio1205-351

See also: Letter by Stern et al.

Toward small-molecule agonists of TNF receptors

 pp353 - 354

Sarah G Hymowitz and Avi Ashkenazi

doi:10.1038/nchembio1205-353

See also: Letter by Fournel et al.

NO link between calorie restriction and mitochondria

 pp355 - 356

Leonard Guarente

doi:10.1038/nchembio1205-355

Lactate transportation is required for lymphocyte activation

 pp356 - 357

Stefan Bröer

doi:10.1038/nchembio1205-356

See also: Letter by Murray et al.

Research Highlights

 p359

doi:10.1038/nchembio1205-359

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Perspective

Photochemical tools for remote control of ion channels in excitable cells

 pp360 - 365

Richard H Kramer, James J Chambers and Dirk Trauner

Published online: 16 November 2005 | doi:10.1038/nchembio750

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Letters

Small molecules that delay S phase suppress a zebrafish bmyb mutant

 pp366 - 370

Howard M Stern, Ryan D Murphey, Jennifer L Shepard, James F Amatruda, Christian T Straub, Kathleen L Pfaff, Gerhard Weber, John A Tallarico, Randall W King and Leonard I Zon

Published online: 13 November 2005 | doi:10.1038/nchembio749

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See also: News and Views by Sidi & Look

Monocarboxylate transporter MCT1 is a target for immunosuppression

 pp371 - 376

Clare M Murray, Raymond Hutchinson, John R Bantick, Graham P Belfield, Amanda D Benjamin, Diana Brazma, Robert V Bundick, I David Cook, Robert I Craggs, Susan Edwards, Leslie R Evans, Richard Harrison, Elain Holness, Andrew P Jackson, Clive G Jackson, Lee P Kingston, Matthew W D Perry, Andrew R J Ross, Paul A Rugman, Sasvinder S Sidhu, Michael Sullivan, David A Taylor-Fishwick, P Craig Walker, Yvonne M Whitehead, David J Wilkinson, Andrew Wright and David K Donald

Published online: 30 October 2005 | doi:10.1038/nchembio744

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See also: News and Views by Bröer

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L

 pp377 - 382

Sylvie Fournel, Sébastien Wieckowski, Weimin Sun, Nathalie Trouche, Hélène Dumortier, Alberto Bianco, Olivier Chaloin, Mohammed Habib, Jean-Christophe Peter, Pascal Schneider, Bernard Vray, René E Toes, Rienk Offringa, Cornelis J M Melief, Johan Hoebeke and Gilles Guichard

Published online: 06 November 2005 | doi:10.1038/nchembio746

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See also: News and Views by Hymowitz & Ashkenazi

Actin is the primary cellular receptor of bistramide A

 pp383 - 388

Alexander V Statsuk, Ruoli Bai, Jeremy L Baryza, Vishal A Verma, Ernest Hamel, Paul A Wender and Sergey A Kozmin

Published online: 13 November 2005 | doi:10.1038/nchembio748

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Article

Analysis of drug-induced effect patterns to link structure and side effects of medicines

 pp389 - 397

Anton F Fliri, William T Loging, Peter F Thadeio and Robert A Volkmann

Published online: 06 November 2005 | doi:10.1038/nchembio747

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