About the cover
December 2005 Volume 1 No 7
Small-molecule suppression of zebrafish mutants. Using a chemical genetic screen, Stern et al. (p 366) identified persynthamide, a compound that suppresses the crash&burn (crb) mutation in zebrafish by inhibiting S phase of the cell cycle (see also News & Views by Sidi & Look, p 351). The image shows zebrafish embryos immunostained with an antibody specific for phosphorylation of Ser10 of histone H3, a marker of mitotic cells. Cover art by Erin Boyle, based on images provided by Christian Straub.
