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Nature Chemical Biology 1, 355 - 356 (2005)
doi:10.1038/nchembio1205-355
NO link between calorie restriction and mitochondria
Leonard Guarente1
- Leonard Guarente is in the Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA. e-mail: leng@mit.edu
Abstract
Sir2 is a key regulator in promoting longevity in response to a low-calorie diet. A new role for nitric oxide in promoting mitochondrial synthesis may be the reason why.
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