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Nature Chemical Biology 1, 244 - 245 (2005)
doi:10.1038/nchembio1005-244

Decoding chemical structures from genomes

Brian O Bachmann1

  1. Brian O. Bachmann is in the Department of Chemistry, Vanderbilt University, 7921 Stevenson Center, Nashville, Tennessee 37235-1822, USA. e-mail: brian.o.bachmann@vanderbilt.edu


Coelichelin is a new tetrapeptide siderophore from Streptomyces coelicolor originally discovered by gene sequence analysis. Surprisingly, this tetrapeptide is assembled by a trimodular nonribosomal peptide synthetase.

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