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Nature Chemical Biology 1, 125 (2005)
doi:10.1038/nchembio0805-125

New screening tools for lead compound identification

Tomi K Sawyer1

  1. Tomi K. Sawyer is at Ariad Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, Massachusetts 01772, USA. e-mail: tomi.sawyer@ariad.com

The identification of promising lead compounds from high-throughput screens is still a very complex problem. A new high-throughput assay for identifying aggregation-based false positives could help.

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