Supplementary information

From the following article

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce, Yaqiao Li, Prakash Jagtap, Noboru Mizushima, Gregory D Cuny, Timothy J Mitchison, Michael A Moskowitz & Junying Yuan

Nature Chemical Biology 1, 112 - 119 (2005) Published online: 29 May 2005

doi:10.1038/nchembio711

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Supplementary Fig. 1

Nec-1(1) specifically and efficiently inhibits apoptosis.

Supplementary Fig. 2

Nec-1 inhibits multiple necroptosis-associated morphological changes.

Supplementary Fig. 3

Additive effects of 7-Cl-Nec-1(3) and zVAD.fmk on inhibition of ischemia-induced neuronal death in vivo.

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