News and Views
Nature Chemical Biology 1, 8 - 9 (2005)
doi:10.1038/nchembio0605-8
Ending the prolonged life of cancer cells
Gerhard Wagner1
- The author is in the Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA. e-mail: wagner@hms.harvard.edu
Abstract
The fate of cells depends on a delicate balance of pro- and anti-apoptotic proteins. Small-molecule inhibitors of anti-apoptotic protein-protein interactions promote apoptosis in cancer cells.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Bcl-2 turns deadlyNature Chemical Biology News and Views (01 Dec 2008)
Death by design: the big debut of small moleculesNature Cell Biology News and Views (01 Feb 2001)
See all 4 matches for News And ViewsRESEARCH
An inhibitor of Bcl-2 family proteins induces regression of solid tumoursNature Letters to Editor (02 Jun 2005)
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamiliesNature Cell Biology Article (01 Dec 2006)
See all 7 matches for Research
